» Clinical Trials: A Methodologic Perspective Second Edition(Wiley Series in Probability and Statistics)
Price: $102.60
Rating: 5.0 / 5.00 (5 reviews)
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Manufacturer: Wiley-Interscience
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Rating: 5.0 / 5.00 (5 reviews)
Usually ships in 24 hours
Manufacturer: Wiley-Interscience
Click to Buy
Clinical Trials: A Methodologic Perspective Second Edition(Wiley Series in Probability and Statistics) Details
Binding: HardcoverDewey Decimal Number: 610.72
EAN: 9780471727811
ISBN: 0471727814
Label: Wiley-Interscience
Manufacturer: Wiley-Interscience
Number Of Items: 1
Number Of Pages: 720
Publication Date: 2005-08-01
Publisher: Wiley-Interscience
Studio: Wiley-Interscience
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Clinical Trials: A Methodologic Perspective Second Edition(Wiley Series in Probability and Statistics) Reviews
Customer Rating:Summary: unusually well-written text on the statistical aspects
Comment: This book is very unique. Basic statistical concepts are clearly presented but only those concepts that are important in clinical trials. The author presents all the issues with clinical trials including ethical issues with some historical perspective. Principles of randomization and statistical design are clearly presented. It offers discussion of Bayesian techniques and meta-analyses, cross-over designs and group sequential methods (interim analyses). For statisticians doing clinical research like myself, this is a valuable reference source.
Customer Rating:
Summary: Clinical Trials: A Methodologic Perspective Second Edition
Comment: This is an excellent book. It outlines the important issues of clinical trials well. It is understandable and thorough. A must for anyone who is interested in actually doing trials. Not a good book for a brief, superficial overview.
Customer Rating:
Summary: presents clinical trials issues and methodology clearly
Comment: This book is very unique. Basic statistical concepts are clearly presented but only those concepts that are important in clinical trials. The author presents all the issues with clinical trials including ethical issues with some historical perspective. Principles of randomization and statistical design are clearly presented. It offers discussion of Bayesian techniques and meta-analyses, cross-over designs and group sequential methods (interim analyses). For statisticians doing clinical research like myself, this is a valuable reference source.
Customer Rating:
Summary: The best start in clinical trial
Comment: The amount of knowledge and the scope of this book are the exact need for the first contact with clinical trials. Yet, it is not a simple or superficial text. Instead, it not only will guide the reader through the basics of trials (and there is so much that is not basic in it) but the author points the reader to hundreds of papers and books that are landmarks. I regard this book itself as one of these landmarks!
Customer Rating:
Summary: Most up-to-date and thorough cover of Clinical Trials
Comment: Covers many aspects of trials (particularly facets of design and analysis)not yet covered by other books, eg randomisation with minimisation, and meta-analysis of trial results. Readable, applicable, practical, good references, well structured.
Editorial Review for Clinical Trials: A Methodologic Perspective Second Edition(Wiley Series in Probability and Statistics):
Learn rigorous statistical methods to ensure valid clinical trialsThis Second Edition of the critically hailed Clinical Trials builds on the text's reputation as a straightforward and authoritative presentation of statistical methods for clinical trials. Readers are introduced to the fundamentals of design for various types of clinical trials and then skillfully guided through the complete process of planning the experiment, assembling a study cohort, assessing data, and reporting results. Throughout the process, the author alerts readers to problems that may arise during the course of the trial and provides commonsense solutions.
The author bases the revisions and updates on his own classroom experience, as well as feedback from students, instructors, and medical and statistical professionals involved in clinical trials. The Second Edition greatly expands its coverage, ranging from statistical principles to controversial topics, including alternative medicine and ethics. At the same time, it offers more pragmatic advice for issues such as selecting outcomes, sample size, analysis, reporting, and handling allegations of misconduct. Readers familiar with the First Edition will discover completely new chapters, including:
* Contexts for clinical trials
* Statistical perspectives
* Translational clinical trials
* Dose-finding and dose-ranging designs
Each chapter is accompanied by a summary to reinforce the key points. Revised discussion questions stimulate critical thinking and help readers understand how they can apply their newfound knowledge, and updated references are provided to direct readers to the most recent literature.
This text distinguishes itself with its accessible and broad coverage of statistical design methods--the crucial building blocks of clinical trials and medical research. Readers learn to conduct clinical trials that produce valid qualitative results backed by rigorous statistical methods.
